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  • May 6
  • 1 min read

Updated: May 18


Nuclear speckles: a fundamental layer of gene regulation.

Hiroe Namba, Sana Mir, Erin L Groce, Katherine A Alexander. Trends in Cell Biology, 2026



Nuclear speckles regulate functional programs in cancer.

Katherine A Alexander, Ruofan Yu, Nicolas Skuli, Nathan J Coffey, Son Nguyen, Christine L Faunce, Hua Huang, Ian P Dardani, Austin L Good, Joan Lim, Catherine Y Li, Nicholas Biddle, Eric F Joyce, Arjun Raj, Daniel Lee, Brian Keith, M Celeste Simon, Shelley L Berger. Nature Cell Biology 27, 322-335, 2025



p53 mediates target gene association with nuclear speckles for amplified RNA expression.

Katherine A Alexander, Allison Cote, Son C Nguyen, Linguo Zhang, Omid Gholamalamdari, Paula Agudelo-Garcia, Enrique Lin-Shiao, K.M.A. Tanim, Joan Lim, Nicholas Biddle, Margaret C Dunagin, Charly R Good, Mariel R Mendoza, Shawn C Little, Andrew Belmont, Eric F Joyce, Arjun Raj, Shelley L Berger. Molecular Cell, Volume 81, Issue 8, 1666-1681.e6, 2021





 
 

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